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Third Wave of COVID-19

Pakistan is in the third grip of Covid-19 and the daily count is rising. Punjab is worst hit this time. The spread of disease is less in other provinces. The larger cities are more prone to be hit by this disease. Since the onset of the Covid-19 medical community has been persuading the people to follow SOPs which include wearing a mask in public, keeping safe distance and washing hands for 20 seconds frequently. Still the humanity is struggling to find out the exact channel of communication. That is why preventive measures are safe to adopt. In view of the pandemic model, there are three players in the spread of an epidemic. These are first victim, the carrier and second victim. Since the elderly people are more prone to catch the disease, countries have started vaccinating them first. Younger people have fewer chances of severe infection. However, they may act as carrier of disease to the older people. Hence, the only solution left is to keep social distance. Third wave is gripping, crippling and debilitating Pakistan, the severity of the disease has manifested itself in rising numbers of Covid-19 infected patients. Once again lockdown has been introduced; the schools, the colleges, the restaurants, the public places, and the working places have come under a halt. Since the initial smart lockdown strategy did not work, the complete lockdown strategy was adopted. Government efforts send a message to the masses to stay on guard.

Pakistan \government has started \ sinopharm and \ astrazeneca vaccination. People should cooperate with government so that this deadly disease may be overcome. WHO has listed Pfizer vaccine BNT 162b2 and Astra Zeneca by Serum Institute of India and SKBio. Besides these two vaccines, there are Chinese vaccines too. Chinese vaccines include Sinopharm, 4Sinovac and Coronavac. Sinopharm is double jab vaccine which is administered two times with a gap of 15 days. The vaccine’s first jab kick starts immunity. The second booster ensures the immunity. Russia has developed Sputnik V. US has also developed Moderna vaccine. The people who have heart conditions and diabetes are required to take extra precaution. We hope that these vaccines would be able to cope with the disease and the world will soon overcome this deadly pandemic.

CT Scan Service Available

Computed Tomography (CT)

Computed tomography, also referred to as CT or CAT, enables others to see what is transpiring inside the human body. It is a diagnostic medical imaging testing use to replicate three-dimensional imaging of the human organs, bones, certain tissues as well as specific blood vessels. These are generated by combining multiple X-rays, which are automatically done by the computer attached during the examination. These cross-sectional images that are generated during this procedure, are reformatted and can be analyzed from different angles which enables medical examiners to have a better approach and understanding towards their patients.  These images can be viewed on films or displayed on screens and media. CT methodology is efficient, painless and the most accurate procedure for problem analysis.  With the advancement in technology, computed tomography is a trusted method to locate the different types of cancers since imaging allows the examiner to confirm the presence of a tumor. It makes it easier to determine the position of the tumor and how menacing it is, depending upon its size and location.  In a certain catastrophic situation, CAT is used to determine the location of internal bleeding regions which allows the doctors to handle them immediately and save the person in distress.

There are various CAT procedures, each having a specific procedure as well as risks. Some computed tomography that is being commonly being used includes

  • CT Scan Abdomen
  • CT Angiography
  • CT Scan Arthrography
  • CT Scan Bones
  • CT Scan Brain/ CT Scan Head
  • CT Scan Chest (CT Scan Lung)
  • CT Scan Neck
  • CT Scan Pelvis
  • CT Scan Renal Stones
  • CT Scan Sinus
  • CT Scan Spine

These are low-dose CAT scans that are offered in many hospitals around the world. As the pandemic is upon us, doctors are mostly focusing on HRCT, as it is one of the most efficient and fastest ways to identify the presence of virus inside the body and how much has it damaged the body.

Chest CT is mainly used to examine any abnormalities found in a regular chest x-ray. It is used to reason the unexplainable behavior that is associated with the lungs somehow, for instance, shortness of breathing or severe chest pains. Chest CT can identify small nodules in the lungs which can identify lung cancer at the very beginning stage. These scans help oncologists to plan their patient’s chemotherapy and see whether they are responding to the treatment. Malignant Tumors, Tuberculosis, Pneumonia, and many other respiratory diseases can be identified using this methodology.

HRCT is a high-resolution computed tomography that identifies disease better than conventional radiology. HRCT is used for the diagnosis and assessment of Interstitial lung diseases, such as pulmonary fibrosis, interstitial pneumonitis, and other generalized lung diseases such as emphysema, bronchiectasis.  Where HRTC is unable to identify the cause of the problem a biopsy is necessary.

To prepare a patient for a CT scan, they are required to wear a medical gown provided by the hospital facilities. All metallic objects that might hinder the scans are required to remove which includes hairpins, piercing, or removable pieces of dental ware. In the case of female patients, they are required to remove their bra as it has metal wires inside them. Few hours before the procedure, doctors ask the patients to abstain from drinking, eating, or consuming anything.  They might alter with the reading of the scan. The medical examiner must be aware of any history of illness that a patient might have, for instance, heart disease, asthma, or thyroid problems. They are required to report any allergies or any sort of medication they might be using. Any of these conditions might increase the risk of an adverse effect. Women should inform the CT technologist if they might be expecting a child shortly soon to prevent any complications during their pregnancies.

After being identified with all the required information for the patient, they are required to move to a separate room where the CT scanner is present. The patient has to lie on a narrow table, strapped to maintain position, which slides them inside the tube of the CT scanner.  X-ray tubes and detectors are located on a tube called a gantry which rotates around the patient.  The workstation is located in a separate room which receives all the imaging being captured by the gantry. The technologist operates the scanner from the control room and monitors your exam in direct visual contact. They will be able to communicate using a speaker and microphone.

Each body part absorbs a different amount of radiation which makes it possible for the doctors to identify the organ.  Several x-ray beams circulate to the patient who absorbs them.  Sometimes the table moves so x rays can make a spiral path for better imaging. Special computers present in the control rooms log in three-dimensional images and their slices are displayed on the monitors. Each slice shows the interior of the body in a detailed manner, giving the human body a multi-dimensional aspect. Each rotation provides multiple imaging resulting in more detail and additional capabilities.

To obtain results, the patient must refer to a radiologist. A radiologist will be supervising the patient’s exams throughout the entire procedure. They will analyze the images obtained from the CAT examination and send an official report who has ordered the examination. If any follow-up examinations are required, the doctor handling the patient’s case will notify them. Follow-up examinations are used to further identify the abnormalities in the patient tomography.  In the case of a recovering patient, they are used to check if the abnormality is stable or changing.

Computed tomography has certain risks. With exposure to an extensive amount of radiation, there is a possibility of cancer. But the benefits of the diagnosis outweigh the chance of having cancer.  The risk of serious allergic reaction to contrast materials that contain iodine is extremely rare, and radiology departments are well-equipped to deal with them. Children are more sensitive to radiation; they should have a CT exam only if it is essential for making a diagnosis and should not have repeated CT exams unless absolutely necessary. CT scans in children should always be done with a low-dose technique. As for unborn children and pregnant women, CT scans are not recommended unless medically necessary, by the approval of a doctor because they might harm the fetus. However, the benefits outweigh the risks here as this procedure is fast as time is of the essence for a patient. Explanatory surgeries are no longer needed to be conducted and the precise location of tumors can easily be located. It is indeed a milestone in medicine.

Covid Vaccination

COVID Vaccination

Vaccine or Inoculation is a basic and successful approach to shield individuals from infections before they interact with the actual illness

A dose of vaccine contains

  • the integer which is killed or weakened bacteria or virus
  • Adjuvants which helps in boosting the immunologic reaction
  • Preservatives and,
  • Stabilizers

HOW DOES THE COVID-19 VACCINE WORK?

The vaccine works by recognizing the invading germ of the bacteria or the virus which thus aids in production of antibodies which are proteins produced by the natural immune system

These antibodies immunity against disease so when the body is in contact with the actual disease it knows how to fight with it

ARE COVID-19 VACCINES SAFE?

Vaccines we see in market has been gone through three phase testing

in PHASE 1 it has been tested on small number of volunteers

in PHASE 2 it has been tested on hundreds of volunteers and

in PHASE 3 it has been tested on thousands of volunteers

All vaccines have passed medical tests and have been approved by Drug Regulatory Authority of Pakistan (DRAP) and WHO under Emergency Utilization Listing (UEL)

TYPES OF COVID-19 VACCINES AVAILABLE:

  • WHOLE VIRUS VACCINE which includes Sinopharm and Sinovac
  • RNA or mRNA VACCINE which include Pfizer-BioNTech, Moderna
  • NON-REPLICATING VIRAL VECTOR which include Oxford-AstraZeneca, Sputnik-V
  • PROTEIN SUBUNIT which includes Novavax

All of them require 2 intramuscular doses.

SIDE EFFECTS OF COVID-19 VACCINE:

Like any other vaccination COVID-19 vaccination shows mild to moderate and short-lasting symptoms of COVID-19 such as

  • Influenza
  • Headache
  • Muscular pain at the injection site
  • Mild diarrhea
  • Fever
  • Fatigue
  • Chills

CAN A PERSON GET COVID EVEN AFTER VACCINATION?

It is not surprising that people are still testing positive for covid-19 after getting vaccinated but the number of such cases is very small because they have developed some immunity so the severity of the illness is very less and much reduced.

VACCINATION CENTRES IN LAHORE:

Govt. of Pakistan is providing free of cost vaccination for citizens above 19 years in different centers

Around 5.36 million doses have been given in Pakistan and 1.29 million people are fully vaccinated

But it is only 0.6 % of the population of Pakistan who has been fully vaccinated

COMMON MISONCEPTION ABOUT COVID-19 VACCINE:

Common myths are rumoring around such as

COVID vaccines alters DNA

COVID vaccines causes infertility

It’s not safe because of quick rollout

Asthma patients, Pregnant women and nursing mothers can’t get the vaccine

COVID vaccine causes COVID-19

You don’t need vaccine if you had COVID

Mask and social distancing are no longer needed after vaccination

 

We are all vulnerable to vaccine misinformation before believing any unsure information check it against any trusted site like www.who.int

hematology lab tests

Lab Testing – COVID-19

The oncoming of Coronavirus has brought forward notions of extreme uncertainty around the world. Issues ranging from health concerns, psychological concerns, to economic impacts, the pandemic continues to leave a mark on the population as a whole. The fight against this virus requires the individuals around the world to take the necessary precautions, test in case of suspicion, and therefore, follow the necessary SOPs to ensure personal safety, as well as the safety of others.

The virus exposure, from its emergence, has increased at such a rate that it is predicted that it is only a matter of time before it would be impacting every individual around the world. Therefore, it is vital for individuals to understand the importance of lab testing and getting a proper diagnosis; to ensure there is no further spread of neither the virus, nor any medical complication from un-identification.

The lab tests available for the virus can be divided into three broad categories: antigen tests, antibody tests, and molecular/PCR tests. These types would be discussed below in further detail.

  1. Antigen Tests:

These are considered to be the rapid diagnosis tests available for the virus. To obtain the sample, a nasopharyngeal swab is taken to find any protein of the virus. The tests are helpful in finding individuals near the infection stage, or at the peak of the infection. A positive aspect of these tests is that they are generally a lot faster and cheaper in providing with the results.

However, the major issue arises with their accuracy. These tests are generally less accurate than the other lab tests that are available. For example, if the individual is not nearing the peak stage of the virus, the result can come back negative, despite the individual actually having the virus. Similarly, along with false negatives, there are problems of false positives as well. The false positives could be from the result of other similar infections, or improper handling methods.

  1. PCR/Molecular Tests:

In the general terms, if we look into the matter, not all molecular tests apply the use of PCR (polymerase chain reaction), but the aspect is vital for the diagnosis of COVID-19. The test works by identifying the genetic makeup of the virus: RNA. The method of collection of the sample is similar to the antigen tests, in which nasopharyngeal swab is taken. The test, however, takes hours to produce the result, but ensures 100% accuracy. This is majorly due to the fact that these tests are highly sensitive in detecting the virus.

However, it needs to be understood that handling the test is a tedious task, and not all carried out tests are perfect. If the molecular test is not maneuvered in the correct manner, the chance of false positives increases to fifteen to twenty percent. The drawback for this test is that even if the individual has recovered from the virus, the test can still detect traces of it, which may lead towards the problem of false positives.

  1. Antibody Tests:

Unlike the previously mentioned two tests, these tests are not used for the diagnosis of the virus. Another name for the test is the serology test. It uses the blood sample of individuals to detect whether the antibodies exist within the bodies that fight off the virus; thus giving insights on the immune systems of the individuals tested. The test can detect if someone had the virus in the past, but is not helpful in finding out current infections. Experts have said that the importance of the test would be generated, after a proper vaccine exists.

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